Franchise TallyYour shortlist

Franchise guide

CVS franchise

No. CVS Health runs its own CVS Pharmacy stores and has no franchise program. Franchised independent pharmacies are the nearest thing.

Updated

US franchises
Not for sale
Largest franchise like it
Good Neighbor Pharmacy 2,204 locations
Typical cost to open
$407K these brands, low end
Cheapest of them
$44K Good Neighbor Pharmacy

How CVS is run

CVS Health had about 9,000 retail locations at the end of 2025, along with more than 1,000 walk-in and primary care clinics. Its annual report describes no franchised stores. (CVS Health annual report, 2025)

Who owns CVS

CVS Health is a public company; its shares trade on the New York Stock Exchange under the symbol CVS. (CVS Health annual report, 2025)

Franchises like CVS

If you want to own a pharmacy business, these franchise brands sell the closest thing to CVS, largest first.

Pharmacy franchises closest to CVS
BrandCost to openFeeRoyaltyLocationsSales a location
Good Neighbor PharmacyFee $0 · Royalty $599 per month$44K–$556K$0$599 per month2,204−71 in 3 yrs–
GNCFee $20K · Royalty 6% · Sales $484K a location$188K–$530K$20K6%1,960−340 in 3 yrs$484K
The Vitamin ShoppeFee $40K · Royalty 5%$493K–$945K$40K5%681−63 in 3 yrs–
The Medicine ShoppeFee $0 · Royalty 3% or qualifying $599 monthly option$521K–$914K$03% or qualifying $599 monthly option244−53 in 3 yrs–
Medicap PharmacyFee $0 · Royalty 3% or qualifying $599 monthly option$521K–$914K$03% or qualifying $599 monthly option83+16 in 3 yrs–
PharmaconicFee $30K · Royalty 3%$322K–$435K$30K3%3+1 in 3 yrs–

Locations are US locations, franchised and company-owned, at the end of the latest year filed. Sales are yearly, before costs, where the brand publishes them.

Good Neighbor Pharmacy is the largest, with 2,204 US locations. Medicap Pharmacy added the most locations, +16 over 3 years. Of the brands that publish sales, GNC reports the most per location, $484K a year. The typical retail franchise starts at $198K to open; see where the money goes.

Sources

  1. CVS Health annual report, 2025