An IV therapy franchise gives fluids, vitamins and electrolytes through a drip, in a lounge where clients sit for under an hour. Clients come for hydration after illness, travel, exercise or a late night, and many brands add vitamin shots, other wellness treatments and memberships for regular visits. Licensed nurses or other medical staff give the drips under a medical director.
The second group are clinics built around something else, such as medical weight loss, hormone therapy or functional medicine, that offer IV therapy beside it. Medical spas built around injectables and lasers are on the med spa franchises page.
The IV therapy franchises
IV hydration bars and clinics
| Brand | Cost to open | Locations | Change |
|---|---|---|---|
| Prime IV Hydration & WellnessA wellness clinic providing IV hydration and related services.$188K–$607K | $188K–$607K | 212 | +164 |
| The DRIPBaRA The DRIPBaR franchisee provides management support for IV vitamin therapy practices, or offers IV therapy where permitted by law.$169K–$400K | $169K–$400K | 126 | +86 |
| Live Hydration SpaA wellness spa offering IV hydration and vitamin therapy, injectables, ionic detox and oxygen therapy.$228K–$396K | $228K–$396K | 32 | – |
| Hydrate IV BarA wellness studio providing IV hydration and related services.$347K–$578K | $347K–$578K | 23 | +13 |
| LiquividaA wellness center offering vitamin IV infusions and anti-aging and medical wellness services.$621K–$1.03M | $621K–$1.03M | 15 | – |
| HydraliveA hydration therapy clinic offering fluids, vitamins and electrolytes.$257K–$496K | $257K–$496K | 4 | – |
| The IV Hub WellnessA clinic offering IV hydration therapy and medical weight loss treatments given by licensed healthcare professionals.$66K–$122K | $66K–$122K | 4 | – |
| DripologyA wellness business offering IV treatments, detox, hair removal, body sculpting, Botox and skincare on site or mobile.$149K–$401K | $149K–$401K | 1 | – |
| IV NutritionA wellness clinic offering vitamin and nutrient therapy through IV drips, injections and oral supplements.$198K–$403K | $198K–$403K | – | – |
Wellness clinics that add IV therapy
| Brand | Cost to open | Locations | Change |
|---|---|---|---|
| Medi-WeightlossA medically supervised weight loss and wellness clinic, with optional IV therapy.$207K–$435K | $207K–$435K | 105 | – |
| LindoraA medical weight loss and wellness clinic offering weight loss plans and medication, hormone therapy, IV therapy and laser treatments.$272K–$492K | $272K–$492K | 31 | – |
| Well InfusedA wellness center offering IV therapies, functional medicine labs, hormone and regenerative therapies through medical providers, plus wellness products.$324K–$1.05M | $324K–$1.05M | 2 | – |
| 10X Health SystemA wellness center offering nutrient IV therapy, genetic and blood testing, supplements, red light therapy and related services.$216K–$523K | $216K–$523K | 1 | – |
What IV therapy franchises cost to open
The typical brand here costs $216K at the low end of its estimate and $492K at the high end. The lowest starting cost is The IV Hub Wellness’s, from $66K. Use each brand’s full range for budgeting: the low end is a small site in a cheaper market.
| Kind | Brands | Typical cost to open |
|---|---|---|
| IV hydration bars and clinics | 9 | $198K–$403K |
| Wellness clinics that add IV therapy | 4 | $244K–$508K |
An IV lounge needs little heavy equipment: recliners, infusion pumps, a clean room to mix drips, and a small clinical fit-out. The build-out of a retail unit is the largest share. Working capital is a large share too, because nurses and a medical director are paid from the first day, before the client base is built.
Fees and royalties
The typical franchise fee is $50K and the typical royalty 7% of sales, plus 2% for marketing. Royalties come off sales before rent, wages or loan payments. The fees and royalties guide compares industries.
What locations sell
Of these brands, 4 publish a comparable yearly sales figure per location; the typical one is $636K. Sales are before costs, so they say nothing on their own about profit.
| Brand | Yearly sales | Sales ÷ cost |
|---|---|---|
| The DRIPBaR2025 | $791K | 2.8× |
| Hydrate IV Bar2025, 12 locations | $656K | 1.4× |
| Prime IV Hydration & Wellness2025, 152 locations | $616K | 1.6× |
| Live Hydration Spa2024, 24 locations | $506K | 1.6× |
Which IV therapy franchises are growing
All 3 brands with three years of location figures grew from 2023 to 2025, a net change of +263 locations between them. The typical one lost 1.1% of its franchised locations a year to closures, terminations and non-renewals, against 3.0% across all franchises. On the SBA Franchise Directory are 7 of the 13, so SBA-backed loans are open to them.
Before you buy
IV therapy is a medical treatment, and states regulate it differently. Ask how the brand meets your state’s rules on who must assess each client before a drip and who may start one, and what the medical director and malpractice insurance cost. Some brands run as a management company supporting a medical practice rather than giving the therapy themselves, which changes what you own.
Ask also how many clients come back each month, since a business built on first visits needs constant marketing, and how the brand buys its fluids and vitamins, and what happens to your schedule if a supplier runs short.
Questions
Do you need to be a nurse or doctor to own an IV therapy franchise?
Usually not. Most brands let a non-medical owner run the business, with a contracted medical director and licensed nurses giving the treatments. A few states require a physician to own the medical practice itself, and then the franchisee owns a management company that runs the rest. Ask the franchisor how its owners are set up in your state.
Does health insurance pay for IV hydration?
Not for elective wellness drips, so clients pay themselves, either per visit or through a monthly membership. That keeps billing simple, with no insurance claims, but it ties sales to what clients choose to spend. Ask existing owners what share of visits comes from members.