A med spa sells cosmetic treatments that need medical staff: injectables such as wrinkle relaxers and fillers, laser hair removal and skin resurfacing, body contouring, and medical-grade facials and peels. A doctor or nurse practitioner oversees the treatments and nurses or other licensed staff give most of them. Many brands sell memberships that spread the cost of regular treatments over the year, which makes revenue steadier.
The second group here are clinics that mix aesthetics with hormone therapy, vitamin shots and other anti-aging care. Brands built mainly around IV drips are on the IV therapy franchises page.
The med spa franchises
Medical spas
| Brand | Cost to open | Locations | Change |
|---|---|---|---|
| dermani MEDSPAA medical spa offering skin rejuvenation, cosmetic injectables and laser hair removal, provided by licensed medical staff.$492K–$906K | $492K–$906K | 30 | +16 |
| ProMD HealthA medical aesthetics practice offering injectables, skin and body treatments and wellness therapies.$197K–$511K | $197K–$511K | 12 | – |
| Youthful BeginningsA medical spa offering injectables, hormone replacement therapy, laser and skin treatments, waxing and weight loss services.$192K–$368K | $192K–$368K | 7 | +4 |
| BYouA medical spa offering laser hair removal, injectables, skin treatments and hair growth procedures.$490K–$917K | $490K–$917K | 6 | – |
| Couture Med SpaA management company for a medical spa offering aesthetic and anti-aging treatments.$1.23M–$2.02M | $1.23M–$2.02M | 6 | – |
| medspa810A medical spa offering injectables, laser treatments and other aesthetic procedures, with skin care products.$476K–$693K | $476K–$693K | 4 | – |
| VIO Med SpaA medical spa offering injectables, body contouring, laser and skin treatments under medical oversight.$794K–$1.23M | $794K–$1.23M | – | – |
Aesthetic and anti-aging clinics
| Brand | Cost to open | Locations | Change |
|---|---|---|---|
| R3VIVEA wellness clinic offering hormone therapy, vitamin infusions and shots, and aesthetic treatments.$262K–$669K | $262K–$669K | 10 | – |
| Hello SkinA management company for a facial longevity clinic offering facial scans, skin rejuvenation and laser treatments.$428K–$795K | $428K–$795K | 0 | – |
What med spa franchises cost to open
The typical brand here costs $476K at the low end of its estimate and $795K at the high end. The lowest starting cost is Youthful Beginnings’s, from $192K. Use each brand’s full range for budgeting: the low end is a small site in a cheaper market.
| Kind | Brands | Typical cost to open |
|---|---|---|
| Medical spas | 7 | $490K–$906K |
| Aesthetic and anti-aging clinics | 2 | $345K–$732K |
Lasers and body contouring machines are the large equipment cost, bought or leased, which is why equipment is a bigger share here than in a day spa. The build-out of private treatment rooms comes next. Working capital matters too: payroll for licensed staff starts before the client list is built.
Fees and royalties
The typical franchise fee is $50K and the typical royalty 6% of sales, plus 1% for marketing. Royalties come off sales before rent, wages or loan payments. The fees and royalties guide compares industries.
What locations sell
One brand here publishes a comparable yearly sales figure per location. Sales are before costs, so they say nothing on their own about profit.
| Brand | Yearly sales | Sales ÷ cost |
|---|---|---|
| dermani MEDSPA2025, 22 locations | $711K | 1× |
Which med spa franchises are growing
All 2 brands with three years of location figures grew from 2023 to 2025, a net change of +20 locations between them. On the SBA Franchise Directory are 3 of the 9, so SBA-backed loans are open to them.
Before you buy
Ask how the brand meets your state’s medical rules. In many states a business that gives injections must be owned or directed by a physician, so the franchise may need a medical director under contract, or a structure where a medical practice gives the treatments and your company runs everything else. Ask what the medical director costs, who carries the malpractice insurance, and who may inject.
Then ask how the brand buys its injectables and lasers, whether you must buy equipment from set suppliers, and how many clients a typical location keeps on a membership after its first year.
Questions
Do med spa clients pay with health insurance?
Rarely. Cosmetic treatments such as injectables, laser hair removal and body contouring aren't covered by health insurance, so clients pay themselves, which is why med spas lean on memberships, packages and payment plans. It also means sales follow household budgets: ask owners how their bookings held up in a slow year.
What is the difference between a med spa and a day spa franchise?
A day spa offers massage, facials and body treatments that licensed estheticians and massage therapists can give without a doctor. A med spa adds treatments that count as medical, such as injectables and many lasers, so it needs medical oversight, costs more to equip and charges far more per visit.